Molecular cloning of feline immunodeficiency virus.
نویسندگان
چکیده
منابع مشابه
Molecular cloning of feline immunodeficiency virus.
Feline immunodeficiency virus (FIV) is a T-lymphotropic retrovirus associated with immunodeficiency and opportunistic infections in cats. The discovery of FIV provides an opportunity for the development of a small animal model for AIDS. To initiate the molecular and biological characterization of FIV, cDNA clones were synthesized and used to isolate a proviral clone of FIV. Molecular cross-hybr...
متن کاملMolecular characterization of feline immunodeficiency virus budding.
Infection of domestic cats with feline immunodeficiency virus (FIV) is an important model system for studying human immunodeficiency virus type 1 (HIV-1) infection due to numerous similarities in pathogenesis induced by these two lentiviruses. However, many molecular aspects of FIV replication remain poorly understood. It is well established that retroviruses use short peptide motifs in Gag, kn...
متن کاملFeline leukemia virus and feline immunodeficiency virus.
Ophthalmic manifestations of FeLV or FIV infection can occur in all ocular tissues and may be manifestations of direct viral effects or secondary to viral-related malignant transformation. Additionally, the manifestations of common feline ophthalmic pathogens may be more severe and poorly responsive to therapy because of the immunosuppressive effects of FeLV or FIV infection. Prompt diagnosis o...
متن کاملFeline leukemia virus & feline immunodeficiency virus.
RISK OF INFECTION/EXPOSURE The risk of infection is higher in younger animals and cats that are in contact with multiple cats (strays). Generally, Feline Leukemia Virus (FeLV) is spread by casual contact between cats although as they age, resistance to infection develops. Feline Immunodeficiency Virus (FIV) is spread more commonly through bite wounds or through sexual behaviour. Exposure occurs...
متن کاملMolecular biology of the feline immunodeficiency virus auxiliary genes.
Introduction Feline immunodeficiency virus (FIV) causes a slowly progressive multiorgan disease in infected cats and shows considerable pathogenic similarities to the human immunodeficiency virus type I (HIV-1i), the causative agent of AIDS (Miyazawa & Mikami, 1993; Pedersen et al., 1987; Yamamoto et al., 1988). It is therefore considered a useful small-animal model for HIV-l-induced AIDS studi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1989
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.86.7.2448